Space RPG? Mass Effect.. and oh boy, that's the only one that even exists
Haha oh wow. Excuse me, I feel the need to carpet photobomb this thread. I see Anachronox was already mentioned, I won't repeat the recommendation. Yes I will: It's great.
As a reminder, these are GOOD space RPGs:
With mods. First one's finished, this one is smarter.
Yes Star Control 2 is an RPG even without a level up system.
And before anyone gets clever, JRPGs are fine.
See previous.
I only exaggerate slightly when I call this the single greatest space RPG ever made. It's clever, is science fiction instead of science fantasy, lets you customize spaceships, has branching paths that affect the plot, is dramatic without being melodramatic and is great. And yeah it was by Platinum and on the DS. Here,
read the review, buy it on Amazon.
And I suppose if you actually want something in the vein of Mass Effect there
Xenoblade Chronicles X, with the caveat that it has a 95% chance of involving actual deicide because it's a Takahashi game.
Bonus round:
It's not set in space, but SMT Strange Journey has an aesthetic right out of the Rocketeer and might as well be on a different planet.