With regards to quests, there has to be more notification given to the player(s).
1) On quest start, not everyone realizes that you can click on the notification in the top left to view the journal entries (or that you can view them from message log window). Perhaps there need be an indication somewhere that you can click on them, or something that just implies, "click me to view."
2) I was surprised when on the third quest, that something was spawned that need be brought back to my home command station. When I realized this was given to me (or rather, in a two-player game, my friend who was host) it was already too late to react. Nothing was ever indicated to us that we came in possession of such an artifact; it would help if the player was actually aware of whatever objectives or units they come into possession, or are tasked with.
Beyond that, I haven't gotten past that point because that's the dead end of the quest line, I suppose, which I dislike because I believe it should be re-doable; of course, not to the point where you can just attempt and re-attempt in frivolity.