Only two bad things happened:
-Got a few identical weapon shops. 5 needles gun, Boarine Shotgun and whatever the third was.
-Got a crash when he reached level 10. Couldn't reproduce it after that though.
Apart from that and the stream killing itself from time to time, it was pretty neat.
Sorry to say he reached an abominable DPS that just melted Terminus, so he couldn't see the new stuff he does.
That's about it. Glad I was able to watch it.
Aye, the DPS is something that may need a bit of a looking at... needs more testing to see just how often it's happening. Not a surprise though, when you add so many items to the game, you're bound to warp things a bit. I did have it happen in a run last night myself, though at the same time I was also doing a lot of min-maxing; not everyone does that.
....also as far as Terminus goes, I got some of the numbers wrong. I realized this last night. Going to fix some of those later. Math is the enemy.
EDIT: One other thing that occurs to me, he was using the Humble mech, I'm guessing? It's possible that may be part of the reason behind the massive DPS, if that's the case. It's certainly had the least playtime compared to all of the others. I still haven't even had that much time with it myself since I usually use the White Gloss during testing runs (because of how average it is).
At the same time though, the Humble mech does seem like it's partly made to be very good at destroying heavy foes. Having some "boss killer" sorts of things in a game like this is unavoidable. There is, for example, a certain drone that serves that purpose, but is damn near useless against normal enemies.
Was he using the Humble mech's energy weapon a lot?