Hm, a bunch of these probably need replacing at this point:
Disarmament, there's no reward worth holding back ALL missiles for the entire floor. You typically miss out on countless opportunities for items (losing WAY more than you could gain from winning that), chances to enter secret/sacrifice rooms, and the ability to defend yourself.
Rush Hour is completely pointless. Unusable. Why is it even here?
No Pain No Gain is not viable anymore, that probably also needs replacing. Trying to do it will just kill you.
Pauper too, maybe. You need a seriously exact amount of credits to do that, depending on what items spawn in shops, AND you have to use a whole bunch of keys to get in the shops to spend money in them. Talk about RNG...