Well, I got to a point where I could start up and see the menu, but all sorts of redrawing issues occurred and the background was white.
When starting it in fullscreen mode, the background would show, but not the menu.
Starting a new game will crash the game on my setup, running OSX10.6 with wine-devel 1.1.36.
I might have a problematic setup, as the Radeon X1600 in my MBP is not very well supported in wine.
It's a bumpy road just to get the menu up, so stick to dual-boot for now.