Yes, I can access message log(read objectives and other tabs), also I can save/quit game or check achievements or settings. Only gameplay is affected by this "freeze" issue (also during pause mode). Also I can't zoom in/out map or move map
I'm playing solo game, it happens in regular campaign and in defence mode. Performace settings are all default - I haven't changed anything, for example in advanced settings - everything is unchecked; graphics section - only "disable new title screen" is checked,nebula intensity - 60 , max loading threads - 220; interface tab - refresh rate - 60, fullscreen - 1280 x 1024