Built up a huge fleet to push for the Advanced Factory. Left the Warp gates up on the way there to keep my AI progress below 250 (at 230 currently).
With the advanced Factory, started building T-Raiders IV and Etherjets IV (for raiding the data center).
After about an hour of consolidation (I now have a nice long tough to defend string of worlds but it appears I'm against the AI opponent that doesn't send waves so that's not as big a deal). I start sending the Raiders and Etherjets towards the 6 Data Center system. In system I find a fortress an ion cannon and about a bazillion snipers. I start taking out roaming troops and send the Etherjets in for the Datacenters. It's a pretty brutal fight and I take out 4 data centers and several turret nodes before being decimated (the system was 3 hops into enemy territory so retreat just seemed silly).
While this is happening, my Scout IVs (Thanks for the advice Chris!) have found the enemy homeworlds.
Current status:
Flagship, Dreadnought, Raid Ships
Laser Turrets, Tractor Mk2, Missile, Basic Turret II, Engineer II
Etherjet III, T-Raider III, Bomber III, Scout III, Fighter II, Cruiser II, Autocannon II
Sitting on (I think) 7k knowledge. It'll probably go into Spider Turrets and reserve the rest for my next ship unlock (which looks like it's going to take a major push to get to.
I currently hold 10 planets, all with 4+ resources. My Starships are at their cap and waiting to push toward the next research station. My main fleet is on their way there. The AI Progress has been knocked back down to 140 (I finished off those warp gates) and I'm feeling a lot more comfortable (I have a stronger fleet AND the enemy attacks are weaker).