Actually, I already find I do not have enough buttons. I move with ESDF, and use all 5 mouse buttons, along with WRTGV for skills. I still find myself having to swap out skills a lot on the skill bar. There are just so many great situation spells I like having immediate access to.
If we could bind the second and third row to keys as well, I'd love it! But, that would definitely be a post-1.0.