Recently read through the patch notes and on Wednesday the 30th there was this:
Some of these may need further balancing to really make them ideal, but these now feel much more like powerups, and you're no longer running into 60-70% of items being just negative effects on you. Instead everything is at least moderately positive despite whatever drawbacks might be attached to the equipment, and the question is instead if the costs and benefits of the equipment fit into your current tactical plan.
On Friday the 1st I found the +6 Expensive facehuggers of Leprosy. Although an amusing name, it has both: +390% damage taken and -205% spell strength.
Unless I'm misinterpreting something this shouldn't be happening anymore.